30th September 2021

A 78-year-old male is seen in the acute medical unit (AMU), having been admitted with a seizure

A 78-year-old male is seen in the acute medical unit (AMU), having been admitted with a seizure. He reports feeling unwell over the past few days, with a fever and rigors. He has a past medical history of hypercholesterolaemia, for which he takes a statin. He has recently returned from a holiday to India. On examination, he appears jaundiced. His observations reveal hypotension and oliguria. Giemsa-stained thick and thin blood smears show Plasmodium falciparum species and high levels of parasitaemia.

Which of the following is the most appropriate management?

Select the SINGLE most appropriate option from the list below. Select ONE option only.