1st April 2022

A 45-year-old male with the karyotype 47,XXY presents to his GP

A 45-year-old male with the karyotype 47,XXY presents to his GP with a 2-month history of feeling tired all the time. He works in an office and is under a lot of stress currently. He has been struggling with painful, swollen joints in his hands, which makes it difficult for him to work. 

What is the most likely cause of his symptoms?

Select the SINGLE most appropriate option from the list below. Select ONE option only.