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27th May 2023
A patient presents to the emergency department following a seizure
A patient presents to the emergency department following a seizure. His partner informs you that he has been feeling unwell in the last few days with a few episodes of loose stool. In the last 24 hours, he has become drowsier, prior to having the seizure. Urine dip is positive for protein and blood. Blood tests show the following:
| Haemoglobin | 90 g/L | (130-180 g/L) |
| Platelets | 25 x 10⁹ | (140-400 x 10⁹) |
| Urea | 10 mmol/L | (2.5-7 mmol/L) |
| Creatinine | 240 μmol/L | (50-120 μmol/L) |
| Bilirubin | 29 μmol/L | (1-17 μmol/L) |
| PT | 12 s | (10-14 s) |
| APTT | 26 s | (22-36 s) |
What of the following is the most likely diagnosis?
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