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1st June 2023
A 23-year-old man attends the minor injury department complaining of a painful, swollen right knee
A 23-year-old man attends the minor injury department complaining of a painful, swollen right knee following a fall onto the same knee during exercise 6 hours earlier. He has an uncomplicated past medical history.
Blood tests reveal:
| Hb | 134 g/l | Males: (135 – 175 g/L) |
| Platelets | 208 x 10⁹/L | (150 – 400 x 10⁹/L) |
| WCC | 8 x 10⁹/L | (4 – 11 x 10⁹/L) |
| Na+ | 134 mmol/L | (135 – 145 mmol/L) |
| K+ | 4.5 mmol/L | (3.5 – 5.0 mmol/L) |
| Urea | 4.5 mmol/L | (2.5 – 6.5 mmol/L) |
| Creatinine | 70 μmol/L | (50 – 120 μmol/L |
| CRP | 6 mg/L | (0 – 10 mg/L) |
| PT | 12.3s | (10.6 – 14.9s) |
| APTT | 52.4s (normalises on 50:50 mixing with donor plasma) | (23.0 – 35.0s) |
| Factor VIII activity level | 12% | |
| Bleeding time | Normal | |
Which of the following is the most likely diagnosis?
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