22nd June 2023

A 67-year-old lady with a history of metastatic breast cancer with bony metastases, presents to the Acute Oncology Service

A 67-year-old lady with a history of metastatic breast cancer with bony metastases, presents to the Acute Oncology Service with a 24-hour history of peripheral paraesthesia and muscle cramps. Her current drug history is letrozole 2.5 mg and denosumab which she receives subcutaneously every 4 weeks and has no known drug allergies. She lives with her partner and is normally independent with a performance status of 0.

Which of the following is most likely to remedy her current symptoms?