23rd June 2023

A 44-year-old previously well woman presents to hospital with fevers and bloody diarrhoea.

A 44-year-old previously well woman presents to hospital with fevers and bloody diarrhoea. Her blood results are below:

Result	Normal reference range
Haemoglobin 88 g/L	115-160 g/L
White cell count 13.51 x 10⁹/L	4.0-11.0 x 10⁹/L
Platelets 75 x 10⁹/L	150-500 x 10⁹/L
Urea 23 mmol/L	2.5-7.0 mmol/L
Creatinine 313 μmol/L (baseline 70 μmol/L)	60-100 μmol/L

Further bloods show a raised bilirubin, raised LDH, low haptoglobins and a negative Coombs test.

Which gastrointestinal pathogen is most associated with the clinical picture above?

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