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23rd June 2023
A 50-year-old woman presents to the emergency department with confusion and a fever.
A 50-year-old woman presents to the emergency department with confusion and a fever. Admission bloods:
| Result | Normal reference range |
|---|---|
| Haemoglobin 90 g/L | 115-160 g/L |
| White cell count 10 x 10⁹/L | 4.0-11.0 x 10⁹/L |
| Platelets 70 x 10⁹/L | 150-500 x 10⁹/L |
| Urea 20 mmol/L | 2.5-7.0 mmol/L |
| Creatinine 250 μmol/L (baseline 70μmol/L) | 60-100 μmol/L |
| Blood film: anaemia, true thrombocytopenia, schistocytes (fragmented red cells), reticulocytes | – |
| ADAMSTS13 activity: low | – |
What is the initial recommended treatment for this condition?
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