26th June 2023

A patient with known HIV presents to ED. She has a 3-month history of drowsiness

A patient with known HIV presents to ED. She has a 3-month history of drowsiness, weight loss and a newly reported headache. She admits that she regularly forgets to take her antiretroviral therapy. An MRI was done on arrival (shown below) and shows multiple contrast enhancing lesions with mass effect.

Patient MRI

What is the most likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.