27th June 2023

Lachlan is a 22-year-old bartender from Sydney. He presents following a seizure and reports that he has had a headache for the past week.

Lachlan is a 22-year-old bartender from Sydney. He presents following a seizure and reports that he has had a headache for the past week. He reports fevers, weight loss and lymphadenopathy over the last few months. MRI brain demonstrates thickening of the dura. Serum beta-D-glucan testing is positive. He is tested for HIV and is found to be positive. CD4+ T-cell count is 70 cells/μL. Which technique is most likely to lead to a diagnosis of the cause?

Select the SINGLE most appropriate option from the list below. Select ONE option only.