9th July 2023

A 42-year-old female presents to the acute take with a blistering rash. On systemic enquiry, she reports that she has been suffering with painful mouth lesions

A 42-year-old female presents to the acute take with a blistering rash. On systemic enquiry, she reports that she has been suffering with painful mouth lesions for the last 4 months, and she first noticed the rash 4 weeks ago. On examination, she is systemically unwell and has a widespread rash over her upper chest consisting of painful erosions and flaccid blisters. You suspect a diagnosis of pemphigus vulgaris. What protein is affected in this condition?

Select the SINGLE most appropriate option from the list below. Select ONE option only.