11th July 2023

A 30-year-old Caucasian woman presents with new skin lesions on her hands

A 30-year-old Caucasian woman presents with new skin lesions on her hands (see image below). Her mother had breast cancer and multiple gastrointestinal polyps. Her sister recently had a skin melanoma excised at the age of 24 and was diagnosed with autism spectrum disorder. On physical examination, the patient is noted to have a high arched palate. Given the history above, you suspect Cowden’s syndrome.

New lesions on the hands

What are the lesions demonstrated in the photograph above?

Select the SINGLE most appropriate option from the list below. Select ONE option only.