Xerostomia | Medibuddy
17th July 2023

Xerostomia

A reduction in salivary gland output into the oral cavity can result in xerostomia, which is defined as the sensation of oral dryness. There are several temporary and permanent causes of xerostomia (see table 3).

Temporary Permanent
Physiological

Psychological (anxiety and depression)

Drugs (many causes! Just a few listed below)

  • Tricyclic antidepressants
  • Diuretics
  • Anticholinergics (atropine, oxybutynin)
  • Antihistamines
  • Opioids
  • Antipsychotics
  • Antiparkinsonian medication

Sialolithiasis

Infections

Sjögren’s syndrome

Diabetes mellitus

Sarcoidosis

Cystic fibrosis

Parkinson’s disease

Bone marrow transplant (60`% of recipients)

Trauma (accidental or postoperative)

Radiation

Table 3: Causes of xerostomia

After physiological xerostomia, the next most common cause is drug-induced xerostomia.

Complications of xerostomia include altered taste, dysphagia, dental caries and an increased risk of oral candidiasis and bacterial infections.

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