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18th July 2023
A 19-year-old man presents to the gastroenterology clinic with a 2-month history of weight loss
A 19-year-old man presents to the gastroenterology clinic with a 2-month history of weight loss, abdominal pain, and bloody diarrhoea up to 6 times per day. He recently received treatment for B12 deficiency from his GP and complains of painful oral mucosal ulceration. Initial blood tests are as follows:
| Haemoglobin | 125 | 130 – 180 g/L | ALT | 30 | <41 U/L |
| White cell count | 13.7 | 4.5 to 11.0 × 10⁹/L | ALP | 110 | 30–130 U/L |
| Platelets | 570 | 140 – 400 x10⁹/L | Albumin | 31 | 35–50 g/L |
| Urea | 6.0 | 2.5 – 7.8 mmol/L | Bilirubin | 15 | <21 μmol/L |
| Creatinine | 75 | 59–104 μmol/L | CRP | 42 | < 5mg/L |
Which of the following investigations is most likely to be diagnostic in this case?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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