24th July 2023

A 42-year-old woman with a background of hypertension presents to A&E

A 42-year-old woman with a background of hypertension presents to A&E with a 1-week history of progressive jaundice. She reports loose stools, which on questioning describes as “different than normal”. There is no associated abdominal or back pain. She has lost around 2 stone in weight over the past couple of months, despite not changing her diet. Blood tests suggest cholestasis.

Which of the following is the best next investigation?

Select the SINGLE most appropriate option from the list below. Select ONE option only.