Opioid Dose Equivalence | Medibuddy
5th January 2024

Opioid Dose Equivalence

If patients become unable to swallow, oral preparations of morphine can be switched to the subcutaneous route and are often given through a syringe driver.

From To Calculation
Oral codeine Oral morphine Divide by 10
Oral tramadol Oral morphine Divide by 10
Oral morphine Subcutaneous morphine Divide by 2
Oral morphine Intravenous or subcutaneous diamorphine Divide by 3
Oral morphine Oral oxycodone Divide by 2
Oral oxycodone Subcutaneous oxycodone Divide by 2

Source: adapted from Scottish Palliative Care Guidelines. Choosing and Changing Opioids [Internet]. [cited 2023 Jul 16]. Available from: https://www.palliativecareguidelines.scot.nhs.uk/guidelines/pain/choosing-and-changing-opioids.aspx

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