11th January 2024

Lung cancer

ILD is an independent risk factor for developing lung malignancy, which could be partially secondary to increased cell damage due to inflammatory nature of the condition. An estimated 15-20% of ILD patients develop lung cancer.
It is often challenging to diagnose, as emerging symptoms are often contributed to the already-known diagnosis of ILD. Constitutional symptoms such as new weight and appetite loss, new haematemesis or chest pain should prompt further investigations with imaging +/- bronchoscopy.
Mesothelioma is a rare but highly aggressive type of lung cancer. Up to 90% of all cases are linked to asbestos exposure. Note that asbestos exposure also increases the risk of other types of cancer.
Perhaps not surprisingly, lung malignancy is associated with higher morbidity and mortality in patients with ILD compared to patients without ILD.

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