5th February 2024

A 21-year-old female presents to the genetics clinic following a diagnosis of osteosarcoma

A 21-year-old female presents to the genetics clinic following a diagnosis of osteosarcoma. Family history reveals that her mother died from glioblastoma at 40. Her brother was diagnosed with rhabdomyosarcoma at the age of 7. Her maternal aunt also underwent a mastectomy at 30 for breast cancer.

Given the likely gene mutation responsible for the family history of cancer, which of the following cell cycle phases does this protein exert its action?

Select the SINGLE most appropriate option from the list below. Select ONE option only.