5th February 2024

A 23-year-old male with Hodgkin’s lymphoma recently commenced his chemotherapy regimen of doxorubicin

A 23-year-old male with Hodgkin’s lymphoma recently commenced his chemotherapy regimen of doxorubicin, bleomycin, vinblastine and dacarbazine. He has developed increasing numbness and tingling, affecting his hands and feet. This had begun during his second cycle, which spontaneously resolved but has worsened since his third cycle. It was felt that this was secondary to his chemotherapy agents.

Given the likely culprit agent, which cell cycle phase does this agent act on?

Select the SINGLE most appropriate option from the list below. Select ONE option only.