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6th February 2024

A patient with cystic fibrosis presents with worsening vision at night to her GP.

A patient with cystic fibrosis presents with worsening vision at night to her GP. On examination, the patient has normal visual fields and reduced acuity but is correctable with her glasses. On examination of the cornea, there are signs of corneal keratitis on fluorescein staining.

What is the most likely deficiency causing this clinical picture?

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