9th February 2024

Somatostatin

Somatostatin is a polypeptide hormone produced by the pancreas and the neurons within the hypothalamus. It suppresses the endocrine and exocrine functions of the pancreas. Along the rest of the digestive tract, it inhibits the secretion of other GI hormones, reducing gastric emptying and smooth muscle contractions. In the CNS, it inhibits the release of prolactin, GNRH and TSH.