16th February 2024

A 12-month-old boy presents with recurrent purulent discharge from his nose

A 12-month-old boy presents with recurrent purulent discharge from his nose. His mother also reports six episodes of purulent ear discharge, requiring antibiotics to settle. He was found to have diffuse eczematous papules throughout his trunk and extremities with areas of excoriation. Blood tests showed low platelet counts with microthrombocytopaenia, reduced immunoglobulins and reduced T-cell and B-cell lymphocytes.

What is the underlying diagnosis?

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