18th February 2024

A 78-year-old female presented to the acute medical unit with shortness of breath and chest pain

A 78-year-old female presented to the acute medical unit with shortness of breath and chest pain and was found to have a haemoglobin level of 45g/L. She was given a blood transfusion. Three minutes into the blood transfusion, she began to feel feverish with chills. She reports associated chest and flank pain. Blood pressure at this time measured 80/50mmHg, and oozing was noted from her cannula site.

Given the likely diagnosis, which hypersensitivity reaction is the underlying pathogenesis for this condition?

Select the SINGLE most appropriate option from the list below. Select ONE option only.