18th February 2024

A 78-year-old male presents to the acute medical unit with tiredness and shortness of breath

A 78-year-old male presents to the acute medical unit with tiredness and shortness of breath. He denies any symptoms suggestive of blood loss, and urinalysis showed increased bilirubin levels. Blood tests showed a low haemoglobin level with increased unconjugated bilirubin levels. Coombs test was positive with negative cold agglutin antibodies.

Given the likely diagnosis, which hypersensitivity reaction is the underlying pathogenesis for this condition?

Select the SINGLE most appropriate option from the list below. Select ONE option only.