26th February 2024

A 54-year-old woman presents to the emergency department with profound confusion, hypothermia, periorbital puffiness and peripheral oedema.

A 54-year-old woman presents to the emergency department with profound confusion, hypothermia, periorbital puffiness and peripheral oedema. She is suspected to be in a myxoedema coma so a levothyroxine bolus is to be administered. The bolus dose required is 300 mcg/kg/hr. The patient weighs 80kg.

At what rate (mg/min) would the pump need to be set?