A 23-year-old woman is seen in A&E with fever, confusion and muscle rigidity. | Medibuddy
27th February 2024

A 23-year-old woman is seen in A&E with fever, confusion and muscle rigidity.

DATE DRUG NAME DOSE ROUTE FREQUENCY Prescriber’s Signature
10/1/21 Gabapentin 300MG ORAL TWICE DAILY DR
10/1/21 DIAZEPAM 10MG PR PRN DR
10/1/21 HALOPERIDOL 5MG ORAL TWICE DAILY DR
10/1/21 LITHIUM 50MG ORAL ONCE DAILY DR
10/1/21 MOCLOBEMIDE 150MG ORAL TWICE DAILY DR

A 23-year-old woman is seen in A&E with fever, confusion and muscle rigidity. She has bipolar disorder and reports having last taken her medication 3 hours ago. On examination she is noted to have hyperreflexia and clonus.  

Her medications are above. 

Which is the most likely cause of her presentation?

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