10th March 2024

Group 5: Multifactorial

This group includes patients with pulmonary hypertension who do not fit into any of the other categories. They can be further subclassified into:

• Haematological diseases 
  • Chronic haemolytic anaemias (sickle cell disease, beta-thalassemia, spherocytosis)
  • Myeloproliferative disorders
• Systemic or metabolic disorders
  • Sarcoidosis
  • Pulmonary Langerhans’ histiocytosis X
  • Neurofibromatosis
  • Glycogen      storage disease
• Complex congenital heart disease except those with PH due to corrected or uncorrected      left to right shunts
• Other (CKD, fibrosing mediastinitis)