4th April 2024

A 42 year old male was recently diagnosed with MEN-2a.

A 42 year old male was recently diagnosed with MEN-2a. Which of the following would most likely be identified during genetic testing?

Select the SINGLE most appropriate option from the list below. Select ONE option only.

Both MEN-2a and MEN-2b are caused by a gain of function mutation in the RET proto-oncogene. The MEN-1 gene mutation predisposes to the development of MEN1 (pancreatic neuroendocrine tumours, hyperparathyroidism and pituitary adenomas). The MEN gene, MEN-2a gene and MEN-2b gene do not exist.