7th April 2024

A 67-year-old lady presents with lethargy and low mood to her GP. Her past medical history includes type 2 diabetes mellitus

A 67-year-old lady presents with lethargy and low mood to her GP. Her past medical history includes type 2 diabetes mellitus, transient ischaemic attack, osteoarthritis and atrial fibrillation (AF). Her regular medications include bisoprolol, simvastatin, amiodarone, metformin, linagliptin, paracetamol and codeine. Her GP suspects amiodarone associated hypothyroidism and refers the patient to Endocrinology. Amiodarone induced hypothyroidism may be explained by which of the following?

Select the SINGLE most appropriate option from the list below. Select ONE option only.