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11th April 2024
A 26-year-old female presents with tiredness, amenorrhoea, and 9kg of unintended weight loss over the past 5 months.
A 26-year-old female presents with tiredness, amenorrhoea, and 9kg of unintended weight loss over the past 5 months. Her observations reveal postural hypotension, and the physical examination is unremarkable. Pregnancy test is negative, and blood results show the following:
| Hb (135-180 g/l) | 109 |
| MCV (80-100fl) | 85 |
| Haematocrit (0.37-0.47) | 0.42 |
| Sodium (133 – 146mmol/l) | 132 |
| Creatinine (53 to 97.2 µmol/L) | 78 |
| ALT 0-35 (IU/l) | 30 |
| HbA1C (20-42mmol/mol) | 40 |
| GnRH | Undetectable |
| Prolactin (<400 mU/l) | 222 |
| TSH (0.17-3.2 uU/l) | 0.12 |
| Free T4 (11-22 pmol/l) | 7.0 |
Which of the following is the most likely diagnosis?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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Complete Guide to Paediatric Surgery ST3 Application and Recruitment in United Kingdom (2026)
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Paediatric Surgery ST3
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