21st April 2024

A 39-year-old woman with no past medical history presents with flu-like illness including headache, myalgia and fever

A 39-year-old woman with no past medical history presents with flu-like illness including headache, myalgia and fever. She has recently returned from a holiday in Indonesia 2 weeks ago, during which she reports swimming in freshwater rivers. On examination, she has hepatosplenomegaly. Blood tests demonstrate eosinophilia and an ALP of 450. She is diagnosed with acute schistosomiasis and treated with praziquantel.

What is the most likely chronic liver sequelae seen in patients who develop chronic schistosomiasis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.