22nd April 2024

Autoimmune, Gastrointestinal & Immunologic Disorders

Sjögren’s syndrome is an autoimmune disorder characterised by dry mouth and dry eyes. The oral manifestations classically include xerostomia, dental caries, oral candidiasis, and mucosal ulcers. These symptoms are a consequence of decreased salivary gland function and can significantly impact oral health and quality of life.

Crohn’s disease can have oral manifestations that include orofacial granulomatosis, which is characterised by lip swelling, facial swelling, oral ulcers, and gingival hyperplasia. These manifestations may precede gastrointestinal symptoms and can aid in early diagnosis.

Oral manifestations of the disease are common in individuals with HIV/AIDS and can include oral candidiasis, oral hairy leukoplakia, periodontal disease, aphthous ulcers, Kaposi’s sarcoma, and salivary gland dysfunction. These manifestations often indicate a compromised immune system and can serve as markers for disease progression.