26th April 2024

A 45-year-old woman presents with a 6-month history of irregular bleeding, especially post-coitally, and a recent episode of pelvic pain.

A 45-year-old woman presents with a 6-month history of irregular bleeding, especially post-coitally, and a recent episode of pelvic pain. On examination, a cervical lesion is visible.

Investigations:

Haemoglobin: 112 g/L (120–160)

White cell count: 9.0 × 10^9/L (4.0–11.0)

Platelets: 210 × 10^9/L (150–400)

Cervical smear: High-grade squamous intraepithelial lesion (HSIL)

Which is the most likely diagnosis?