26th April 2024

A 68-year-old man presents with a 6-month history of progressive dyspepsi and early satiety.

A 68-year-old man presents with a 6-month history of progressive dyspepsi and early satiety. He mentions a recent change in his appetite and occasional vomiting after meals. On examination, he has mild epigastric tenderness. He has a history of chronic gastritis.

Investigations:

Haemoglobin: 110 g/L (130–180)

White cell count: 6.2 × 10^9/L (4.0–11.0)

Platelets: 210 × 10^9/L (150–400)

Upper gastrointestinal endoscopy: Ulcerated mass in the stomach

Biopsy of mass: Adenocarcinoma

Which is the most likely diagnosis?