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26th April 2024
A 48-year-old woman presents with a history of rapid weight gain over the last six months.
A 48-year-old woman presents with a history of rapid weight gain over the last six months. She also complains of muscle weakness and easy bruising. Recently, she has noticed increased hair growth on her face and body. Her menstrual cycle has become irregular. On examination, she exhibits central obesity and facial plethora. Her blood pressure is 160/100 mmHg.
Investigations:
Plasma ACTH: Low
Dexamethasone suppression test: No suppression of cortisol
Serum testosterone: Slightly elevated
Which is the most likely diagnosis?
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