29th April 2024

A 30-year-old construction worker presents with weakness in his right hand and wrist for the past two weeks.

A 30-year-old construction worker presents with weakness in his right hand and wrist for the past two weeks. He reports that he recently spent several hours continuously operating a heavy drill. He has noticed difficulty in extending his wrist and fingers, and he is unable to grip objects firmly. On examination, there is evident muscle wasting at the base of his thumb.

Which is the most likely diagnosis?