5th May 2024

A 45-year-old man presents with a 10-day history of increasing pain and swelling in his right lower leg.

A 45-year-old man presents with a 10-day history of increasing pain and swelling in his right lower leg. He recalls a minor injury to the area two weeks ago. He has no significant medical history and takes no regular medications. Examination reveals erythema, warmth, and tenderness over the mid-shaft of the tibia. He is afebrile and otherwise systemically well. Blood tests show elevated inflammatory markers. A diagnosis of acute peripheral osteomyelitis is considered.

Which is the most appropriate initial management for his condition?