23rd August 2024

A 25-year-old female presents to her neurologist with fatigue, muscle weakness and blurred vision in her right eye

A 25-year-old female presents to her neurologist with fatigue, muscle weakness and blurred vision in her right eye. She has had similar attacks twice before. Her MRI shows periventricular plaques, and she is diagnosed with multiple sclerosis. She is given IV methylprednisolone and the plan is to start her on natalizumab.

What is the most serious complication of natalizumab use?

Select the SINGLE most appropriate option from the list below. Select ONE option only.