9th September 2024

An 80-year-old male has been referred to ambulatory care with dark urine and marked myalgia

An 80-year-old male has been referred to ambulatory care with dark urine and marked myalgia. He has a past medical history of myocardial infarction and diabetes for which he takes aspirin, bisoprolol, ramipril, furosemide and simvastatin. Plasma creatinine kinase is 4200 U/l (normal 55-170) and IV fluids have been commenced. Which one of the following has most likely interacted with simvastatin to contribute to this presentation?

Select the SINGLE most appropriate option from the list below. Select ONE option only.