15th September 2024

Causes of GH deficiency

Congenital	GH and GHRH gene defects
Hypothalamic-pituitary disease	Tumours (adenomas, craniopharyngiomas, meningiomas)
	Inflammatory conditions (sarcoidosis, histiocytosis, amyloidosis)
	Infections (tuberculosis, toxoplasmosis, Pneumocystis pneumonia, other fungal infections)
	Vascular (pituitary apoplexy, Sheehan’s syndrome, subarachnoid haemorrhage)
	Iatrogenic (surgical trauma, irradiation, octreotide, pembrolizumab)
	Other (traumatic brain injury)

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