17th February 2025

A 65-year-old woman is seen in the haematology clinic for routine follow up of her monoclonal gammopathy of undetermined significance (MGUS).

A 65-year-old woman is seen in the haematology clinic for routine follow up of her monoclonal gammopathy of undetermined significance (MGUS). She also has a background of obesity and hypertension. 

She is noted to have facial swelling, predominantly on the left and affecting the lips and eyelids. She says she has been having this swelling episodically for the last few months. The episodes come on over 1-2 hours, last for up to three days, and are associated with diarrhoea. She has not noted any specific trigger and has not sought medical advice.

Blood tests are sent to investigate these episodes.

Which set of results would be most consistent with this history?

Select the SINGLE most appropriate option from the list below. Select ONE option only.