17th February 2025

A 28-year-old woman presents to a respiratory clinic with recurrent upper and lower respiratory tract infections.

A 28-year-old woman presents to a respiratory clinic with recurrent upper and lower respiratory tract infections. She has a CXR and subsequent CT chest, which shows evidence of bronchiectasis and dextrocardia. On further enquiry, you note that she also suffers with hearing difficulties and subfertility. Which of the following investigations is most likely to aid diagnosis of this patient’s underlying condition? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.