19th February 2025

A patient is being investigated for hypercalcaemia. She has a background of renal cell carcinoma, type 2 diabetes

A patient is being investigated for hypercalcaemia. She has a background of renal cell carcinoma, type 2 diabetes, chronic kidney disease and gastro-oesophageal reflux disease.

Bloods reveal: Na 136 mmol/L (133-146 mmol/L), K 4.2 mmol/L (3.5-5.3 mmol/L), Creatinine 72 µmol/L (45-104 µmol/L), Urea 2.8 mmol/L (2.5-7.8 mmol/L),  Calcium 3.23 mmol/L (2.20-2.60 mmol/L), Phosphate 0.72 mmol/L (0.80-1.50 mmol/L), PTH 3 pg/mL (10-55 pg/mL).

What is the most likely cause of her hypercalcaemia?

Select the SINGLE most appropriate option from the list below. Select ONE option only.