19th February 2025

A 39-year-old woman presents to her GP with weight gain, early satiety and abdominal swelling

A 39-year-old woman presents to her GP with weight gain, early satiety and abdominal swelling. She has a BMI of 35 and a past medical history of gout, for which she uses regular naproxen. Imaging reveals a large cystic mass of 25 cm x 29 cm within her abdomen. Biopsy results reveal a germ cell tumour. She is referred to the oncology team who plan to start chemotherapy.

Which of the following would not increase her risk of tumour lysis syndrome?

Select the SINGLE most appropriate option from the list below. Select ONE option only.