19th February 2025

A patient with idiopathic pulmonary hypertension who did not show a positive response to vasoreactivity testing presents to your clinic.

A patient with idiopathic pulmonary hypertension who did not show a positive response to vasoreactivity testing presents to your clinic. At the time of diagnosis, they were very symptomatic with WHO functional class IV and were considered high risk. They were started on optimal medical therapy with triple therapy. Despite this, they continue to have ongoing symptoms with minimal improvement of treatment. What would be the next step in management of this patient?

Select the SINGLE most appropriate option from the list below. Select ONE option only.