24th February 2025

A 70-year-old man with chronic gout is currently hospitalised with a severe AKI due to obstructive uropathy, requiring filtration on ICU whilst nephrostomies are planned.

A 70-year-old man with chronic gout is currently hospitalised with a severe AKI due to obstructive uropathy, requiring filtration on ICU whilst nephrostomies are planned. He usually takes allopurinol as a urate-lowering measure, which has been continued at a reduced dose based on his creatinine clearance. Unfortunately, he develops an attack of gout. What should happen with his allopurinol, and how should this episode of gout be treated?

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