25th February 2025

A patient is started on treatment for Lyme disease with doxycycline.

A patient is started on treatment for Lyme disease with doxycycline. Two hours later, they experience a headache and myalgia, and feel flushed and ‘generally unwell’. 

Obs show: HR 100 BP 121/86 RR 22 Sats 98% Temp 37.9.

What is the likely cause?

Select the SINGLE most appropriate option from the list below. Select ONE option only.