A 65-year-old female is referred to rheumatology clinic with joint pains and generalised aches.
A 65-year-old female is referred to rheumatology clinic with joint pains and generalised aches. She is also having intermittent fevers.
She has a past medical history of hypertension, which has been refractory to most agents.
She takes amlodipine, ramipril and bendroflumethiazide and was recently started on hydralazine.
Blood tests taken in clinic are shown below:
| Normal range | ||
|---|---|---|
| Hb | 115 | (135-170) |
| WCC | 5.4 | (3.5-11.0) |
| Plt | 360 | (140-400) |
| Neut | 3.4 | (1.7-7.5) |
| ESR | 75 | (0.9-1.8) |
| Na | 141 | (135-145) |
| K | 43 | (3.5-5.1) |
| Urea | 4.7 | (2.9-8.2) |
| Creat | 75 | (66-112) |
| eGFR | >90 | |
| CRP | 2 | (0-5) |
| ANA | Positive, titre 1:640 |
Which antibody is most likely to be positive?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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