27th February 2025

A 33-year-old lady is reviewed in clinic. She has a new diagnosis of metastatic breast cancer

A 33-year-old lady is reviewed in clinic. She has a new diagnosis of metastatic breast cancer (with metastases to two ipsilateral ribs). She has no other past medical history. She is relatively asymptomatic other than dull right-sided rib/breast tenderness and some weight loss due to poor appetite. She has hormone-negative and HER2 receptor-negative breast cancer. Her tumour is PD-L1 positive and she is BRCA negative. What is the most appropriate treatment option?

Select the SINGLE most appropriate option from the list below. Select ONE option only.