11th May 2025

A 47-year-old woman is diagnosed with idiopathic pulmonary hypertension.

A 47-year-old woman is diagnosed with idiopathic pulmonary hypertension. She is under the care of a specialist centre within the UK. She described feeling breathless and quickly tires when performing daily activities such as walking to the toilet and preparing food with occasional breathlessness at rest. On examination she has a raised JVP and pedal oedema. Her 6-minute walk distance is 160 metres and her BNP is 330 nanograms/mL Vasodilator testing is performed and is negative.  What is the most likely pharmacological agent to be started in her case? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.