11th May 2025

A 52-year-old woman with idiopathic pulmonary hypertension is under the care of a specialist centre.

A 52-year-old woman with idiopathic pulmonary hypertension is under the care of a specialist centre. She reports feeling breathless on mild exertion including getting dressed in the morning, despite general supportive management strategies. After having a negative result to vasodilator testing, the decision is made to start her on Bosentan. Which of the following is the mechanism of action of Bosentan? 

Select the SINGLE most appropriate option from the list below. Select ONE option only